I do not think that many people will find this useful. However there is some solution for you.

You can store configuration to INI file, duplicate it and make two (desktop) icons, each using different configuration file (/ini switch). In one you can set interface to "norton" and setup session you want to use with that interface. In the latter you can do the same for "explorer" interface.

For some servers the work I do makes more sense to use the explorer-style view, for others I prefer the dual-window view. Can we have Winscp updated in the future to support different selections for different saved sessions?