Short answer, No. Not according to the documentation for the .NET & COM Library; However it does look like you can do it with VBScript and VBA .
WinSCP .NET Assembly and COM Library
The WinSCP .NET assembly winscpnet.dll is a .NET wrapper around WinSCP’s scripting interface that allows your code to connect to a remote machine and manipulate remote files over SFTP, FTP, WebDAV and SCP sessions from .NET languages, such as C#, VB.NET, and others, or from environments supporting .NET, such as PowerShell, SQL Server Integration Services (SSIS), ASP.NET and Microsoft Azure WebSite.
The assembly is also exposed to COM, and as such it can be used from variety of other programming languages and development environments–e.g., WSH-hosted active scripting languages like JScript and VBScript, Visual Basic for Applications (VBA), Perl, and Python.