Saving problem when using Notepad++ with WinSCP

When I set Notepad++ as a default editor for WinSCP and open one remote file at a time, it works just fine.
When I open multiple remote files and try to save any other than the first one, I get a message:
“The file cannot be saved and it may be protected. Do you want to launch Notepad++ in Administrator mode?”
This combination used to work just fine in my previous pc about one year ago.

Now I’m using WinSCP’s internal editor and it works fine but I’d prefer using Notepad++.

Is this more like Notepad++ problem than WinSCP problem? Any ideas how to fix it?

The problem seems to appear only with 64-bit version of Notepad++. I changed to 32-bit version and it works fine.

I cannot reproduce the problem. If you face it again, let us know.

In WinSCP settings, go to "storage" and check "keep temporary copies of remote files in deterministic paths". It worked for me.