Default Profile & Error At One Site Setting Time or Permissions

Default Profile, can it be bound it to a site?

Error - there is only one site that I'm not able to upload w/out error and it's a site I can't test, so each time 2x's a month I try to change winscp preferences and yet the error remains, what should I do?

Sorry, I do not understand what you ask for.

yeah, I've not been able to catch it, but I'm asking two questions

1) Default profile, |Preferences |Transfer |Default, how to bind the setting under default that was defined under the Site to the Site when connecting/ed ?

2) I've seen this error somewhere on the interweb for winSCP, it's either trying to set/preserve the time stamp or set permissions and the problem only occurs when I connect to one site; which I cannot test; so once a month I submit two files and get this error and each time I try different setting for the 2nd file, but to wit not been able to resolve.

1) Default profile, |Preferences |Transfer |Default, how to bind the setting under default that was defined under the Site to the Site when connecting/ed ?

Are you looking for this?
https://winscp.net/eng/docs/transfer_settings#presets

2) I've seen this error somewhere on the interweb for winSCP, it's either trying to set/preserve the time stamp or set permissions and the problem only occurs when I connect to one site; which I cannot test; so once a month I submit two files and get this error and each time I try different setting for the 2nd file, but to wit not been able to resolve.

This one?
https://winscp.net/eng/docs/message_preserve_time_perm

Yes, thanks...!
I'll give it a try next month, wish me luck...!